Arsenal Football Club was founded in 1886 and, in 1893, became the first club from the south of England to join the Football League. In the 1930s they won their first major trophies: five League Championship titles and two FA Cup trophies. After a lean period in the post-war years they became the second club of the 20th century to win the League and FA Cup Double, in the 1970–71 season, and in the 1990s and 2000s recorded a series of successes – during this time Arsenal won a Cup Double, two further League and FA Cup Doubles, and became the first London club to reach the UEFA Champions League Final.

The club's colours, traditionally red and white, have evolved over time. Similarly, the club have moved location; founded in Woolwich, south-east London, in 1913 they moved north across the city to Arsenal Stadium, in Highbury. In 2006 they made a shorter move, to the Emirates Stadium in nearby Holloway.

Arsenal have an estimated 27 million supporters worldwide, and the fans have long-standing rivalries with several other clubs; the most notable of these is with neighbours Tottenham Hotspur, with whom they regularly contest the North London derby. Arsenal are also the third most valuable club in the world as of 2010, valued at $1.2 billion. The club have regularly featured in portrayals of football in British culture. Arsenal Ladies are the most successful English club in women's football and are also affiliated with the club.

Arsenal Football Club started out as Dial Square in 1886 by workers at the Royal Arsenal in Woolwich, south-east London, and was renamed Royal Arsenal shortly afterwards. The club was renamed again to Woolwich Arsenal after turning professional in 1891. The club became the first southern member of the Football League in 1893, starting out in the Second Division, and won promotion to the First Division in 1904. The club's relative geographic isolation resulted in lower attendances than those of other clubs, which led to the club becoming mired in financial problems and effectively bankrupt by 1910, when they were taken over by local businessman Henry Norris. Norris sought to move the club elsewhere, and in 1913, soon after relegation back to the Second Division, Arsenal moved to the new Arsenal Stadium in Highbury, North London; they dropped "Woolwich" from their name the following year. Arsenal only finished in fifth place in 1919, but were nevertheless elected to rejoin the First Division at the expense of local rivals Tottenham Hotspur, by reportedly dubious means.

Arsenal appointed Herbert Chapman as manager in 1925. Having already won the league twice with Huddersfield Town in 1923–24 and 1924–25 (see Seasons in English football), Chapman brought Arsenal their first period of major success. His revolutionary tactics and training, along with the signings of star players such as Alex James and Cliff Bastin, laid the foundations of the club's domination of English football in the 1930s. Under his guidance Arsenal won their first major trophies – victory in the 1930 FA Cup Final preceded two League Championships, in 1930–31 and 1932–33. In addition, Chapman was behind the 1932 renaming of the local London Underground station from "Gillespie Road" to "Arsenal", making it the only Tube station to be named specifically after a football club.

Chapman died suddenly of pneumonia in early 1934, leaving Joe Shaw and George Allison to carry on his successful work. Under their guidance, Arsenal won three more titles, in 1933–34, 1934–35 and 1937–38, and the 1936 FA Cup. As key players retired, Arsenal had started to fade by the decade's end, and then the intervention of the Second World War meant competitive professional football in England was suspended.

After the war, Arsenal enjoyed a second period of success under Allison's successor Tom Whittaker, winning the league in 1947–48 and 1952–53, and the FA Cup in 1950. Their fortunes waned thereafter; unable to attract players of the same calibre as they had in the 1930s, the club spent most of the 1950s and 1960s in trophyless mediocrity. Even former England captain Billy Wright could not bring the club any success as manager, in a stint between 1962 and 1966.

Arsenal began winning silverware again with the surprise appointment of club physiotherapist Bertie Mee as manager in 1966. After losing two League Cup finals, they won their first European trophy, the 1969–70 Inter-Cities Fairs Cup. This was followed by an even greater triumph: their first League and FA Cup double in 1970–71. This marked a premature high point of the decade; the Double-winning side was soon broken up and the following decade was characterised by a series of near misses. Arsenal finished as First Division runners-up in 1972–73, lost three FA Cup finals, in 1972, 1978 and 1980, and lost the 1980 Cup Winners' Cup final on penalties. The club's only success during this time was a last-minute 3–2 victory over Manchester United in the 1979 FA Cup Final, widely regarded as a classic.

The return of former player George Graham as manager in 1986 brought a third period of glory. Arsenal won the League Cup in 1986–87, Graham's first season in charge. This was followed by a League title win in 1988–89, won with a last-minute goal in the final game of the season against fellow title challengers Liverpool. Graham's Arsenal won another title in 1990–91, losing only one match, won the FA Cup and League Cup double in 1993, and a second European trophy, the Cup Winners' Cup, in 1994. Graham's reputation was tarnished when he was found to have taken kickbacks from agent Rune Hauge for signing certain players, and he was dismissed in 1995. His replacement, Bruce Rioch, lasted for only one season, leaving the club after a dispute with the board of directors.

The club's success in the late 1990s and 2000s owed a great deal to the 1996 appointment of Arsène Wenger as manager. Wenger brought new tactics, a new training regime and several foreign players who complemented the existing English talent. Arsenal won a second League and Cup double in 1997–98 and a third in 2001–02. In addition, the club reached the final of the 1999–2000 UEFA Cup (losing on penalties to Galatasaray), were victorious in the 2003 and 2005 FA Cups, and won the Premier League in 2003–04 without losing a single match, an achievement which earned the side the nickname "The Invincibles"; in all, the club went 49 league matches unbeaten, a national record.